Ontology highlight
ABSTRACT:
SUBMITTER: Fenn S
PROVIDER: S-EPMC3117639 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Fenn Sebastian S Breitsprecher Dennis D Gerhold Christian B CB Witte Gregor G Faix Jan J Hopfner Karl-Peter KP
The EMBO journal 20110415 11
Nuclear actin and actin-related proteins (Arps) are integral components of various chromatin-remodelling complexes. Actin in such nuclear assemblies does not form filaments but associates in defined complexes, for instance with Arp4 and Arp8 in the INO80 remodeller. To understand the relationship between nuclear actin and its associated Arps and to test the possibility that Arp4 and Arp8 help maintain actin in defined states, we structurally analysed Arp4 and Arp8 from Saccharomyces cerevisiae a ...[more]