Gastric motor disturbances in patients with idiopathic rapid gastric emptying.

ABSTRACT:

Background

The mechanisms of 'idiopathic' rapid gastric emptying, which are associated with functional dyspepsia and functional diarrhea, are not understood. Our hypotheses were that increased gastric motility and reduced postprandial gastric accommodation contribute to rapid gastric emptying.

Methods

Fasting and postprandial (300kcal nutrient meal) gastric volumes were measured by magnetic resonance imaging (MRI) in 20 healthy people and 17 with functional dyspepsia; seven had normal and 10 had rapid gastric emptying. In 17 healthy people and patients, contractility was analyzed by spectral analysis of a time-series of gastric cross-sectional areas. Logistic regression models analyzed whether contractile parameters, fasting volume, and postprandial volume change could discr

SUBMITTER: Bharucha AE 

PROVIDER: S-EPMC3117921 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature