Dataset Information

Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.

ABSTRACT: AIM:To perform a genetic characterization of 7 skeletons from medieval age found in a burial site in the Aragonese Pyrenees. METHODS:Allele frequencies of autosomal short tandem repeats (STR) loci were determined by 3 different STR systems. Mitochondrial DNA (mtDNA) and Y-chromosome haplogroups were determined by sequencing of the hypervariable segment 1 of mtDNA and typing of phylogenetic Y chromosome single nucleotide polymorphisms (Y-SNP) markers, respectively. Possible familial relationships were also investigated. RESULTS:Complete or partial STR profiles were obtained in 3 of the 7 samples. Mitochondrial DNA haplogroup was determined in 6 samples, with 5 of them corresponding to the haplogroup H and 1 to the haplogroup U5a. Y-chromosome haplogroup was determined in 2 samples, corresponding to the haplogroup R. In one of them, the sub-branch R1b1b2 was determined. mtDNA sequences indicated that some of the individuals could be maternally related, while STR profiles indicated no direct family relationships. CONCLUSIONS:Despite the antiquity of the samples and great difficulty that genetic analyses entail, the combined use of autosomal STR markers, Y-chromosome informative SNPs, and mtDNA sequences allowed us to genotype a group of skeletons from the medieval age.

SUBMITTER: Nunez C

PROVIDER: S-EPMC3118721 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.

Núnéz Carolina C Sosa Cecilia C Baeta Miriam M Geppert Maria M Turnbough Meredith M Phillips Nicole N Casalod Yolanda Y Bolea Miguel M Roby Rhonda R Budowle Bruce B Martínez-Jarreta Begona B

Croatian medical journal 20110601 3

<h4>Aim</h4>To perform a genetic characterization of 7 skeletons from medieval age found in a burial site in the Aragonese Pyrenees.<h4>Methods</h4>Allele frequencies of autosomal short tandem repeats (STR) loci were determined by 3 different STR systems. Mitochondrial DNA (mtDNA) and Y-chromosome haplogroups were determined by sequencing of the hypervariable segment 1 of mtDNA and typing of phylogenetic Y chromosome single nucleotide polymorphisms (Y-SNP) markers, respectively. Possible familia ...[more]

PMID: 21674829

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Dataset Information

Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.

Publications

Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.

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