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Baculovirus: molecular insights on their diversity and conservation.


ABSTRACT: The Baculoviridae is a large group of insect viruses containing circular double-stranded DNA genomes of 80 to 180?kbp. In this study, genome sequences from 57 baculoviruses were analyzed to reevaluate the number and identity of core genes and to understand the distribution of the remaining coding sequences. Thirty one core genes with orthologs in all genomes were identified along with other 895 genes differing in their degrees of representation among reported genomes. Many of these latter genes are common to well-defined lineages, whereas others are unique to one or a few of the viruses. Phylogenetic analyses based on core gene sequences and the gene composition of the genomes supported the current division of the Baculoviridae into 4 genera: Alphabaculovirus, Betabaculovirus, Gammabaculovirus, and Deltabaculovirus.

SUBMITTER: Miele SA 

PROVIDER: S-EPMC3119482 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Baculovirus: molecular insights on their diversity and conservation.

Miele Solange Ana Belen SA   Garavaglia Matías Javier MJ   Belaich Mariano Nicolás MN   Ghiringhelli Pablo Daniel PD  

International journal of evolutionary biology 20110411


The Baculoviridae is a large group of insect viruses containing circular double-stranded DNA genomes of 80 to 180 kbp. In this study, genome sequences from 57 baculoviruses were analyzed to reevaluate the number and identity of core genes and to understand the distribution of the remaining coding sequences. Thirty one core genes with orthologs in all genomes were identified along with other 895 genes differing in their degrees of representation among reported genomes. Many of these latter genes  ...[more]

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