Ontology highlight
ABSTRACT:
SUBMITTER: Dinstein I
PROVIDER: S-EPMC3119852 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Dinstein Ilan I Pierce Karen K Eyler Lisa L Solso Stephanie S Malach Rafael R Behrmann Marlene M Courchesne Eric E
Neuron 20110601 6
Autism is often described as a disorder of neural synchronization. However, it is unknown how early in development synchronization abnormalities emerge and whether they are related to the development of early autistic behavioral symptoms. Here, we show that disrupted synchronization is evident in the spontaneous cortical activity of naturally sleeping toddlers with autism, but not in toddlers with language delay or typical development. Toddlers with autism exhibited significantly weaker interhem ...[more]