Remodeling the cardiac transcriptional landscape with diet.
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ABSTRACT:
SUBMITTER: Luczak ED
PROVIDER: S-EPMC3121157 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Publications
Remodeling the cardiac transcriptional landscape with diet.
Luczak Elizabeth D ED Barthel Kristen K B KK Stauffer Brian L BL Konhilas John P JP Cheung Tom H TH Leinwand Leslie A LA
Physiological genomics 20110412 12
The perception that soy food products and dietary supplements will have beneficial effects on cardiovascular health has led to a massive consumer market. However, we have previously noted that diet profoundly affects disease progression in a genetic model of hypertrophic cardiomyopathy (HCM). In this model, a soy-based diet negatively impacts cardiac function in male mice. Given the frequent connection between functional changes and transcriptional changes, we investigated the effect of diet (so ...[more]
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2022-07-01 | GSE205734 | GEO