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Chelated ruthenium catalysts for Z-selective olefin metathesis.

ABSTRACT: We report the development of ruthenium-based metathesis catalysts with chelating N-heterocyclic carbene (NHC) ligands that catalyze highly Z-selective olefin metathesis. A very simple and convenient procedure for the synthesis of such catalysts has been developed. Intramolecular C-H bond activation of the NHC ligand, promoted by anion ligand substitution, forms the appropriate chelate for stereocontrolled olefin metathesis.

SUBMITTER: Endo K

PROVIDER: S-EPMC3121191 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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Chelated ruthenium catalysts for Z-selective olefin metathesis.

Endo Koji K Grubbs Robert H RH

Journal of the American Chemical Society 20110512 22

We report the development of ruthenium-based metathesis catalysts with chelating N-heterocyclic carbene (NHC) ligands that catalyze highly Z-selective olefin metathesis. A very simple and convenient procedure for the synthesis of such catalysts has been developed. Intramolecular C-H bond activation of the NHC ligand, promoted by anion ligand substitution, forms the appropriate chelate for stereocontrolled olefin metathesis. ...[more]

PMID: 21563826

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