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Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan.

ABSTRACT: Multilocus sequence typing of Borrelia garinii isolates from humans and comparison with rodent and tick isolates were performed. Fifty-nine isolates were divided into two phylogenetic groups, and an association was detected between clinical and rodent isolates, suggesting that, in Japan, human-pathogenic B. garinii comes from rodents via ticks.

SUBMITTER: Takano A

PROVIDER: S-EPMC3122701 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature

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Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan.

Takano Ai A Nakao Minoru M Masuzawa Toshiyuki T Takada Nobuhiro N Yano Yasuhiro Y Ishiguro Fubito F Fujita Hiromi H Ito Takuya T Ma Xiaohang X Oikawa Yozaburo Y Kawamori Fumihiko F Kumagai Kunihiko K Mikami Toshiyuki T Hanaoka Nozomu N Ando Shuji S Honda Naoko N Taylor Kyle K Tsubota Toshio T Konnai Satoru S Watanabe Haruo H Ohnishi Makoto M Kawabata Hiroki H

Journal of clinical microbiology 20110316 5

Multilocus sequence typing of Borrelia garinii isolates from humans and comparison with rodent and tick isolates were performed. Fifty-nine isolates were divided into two phylogenetic groups, and an association was detected between clinical and rodent isolates, suggesting that, in Japan, human-pathogenic B. garinii comes from rodents via ticks. ...[more]

PMID: 21411595

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