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Fatal cerebral phaeohyphomycosis in an immunocompetent individual due to Thielavia subthermophila.

ABSTRACT: We report the first case of fatal brain infection in an Indian farmer caused by Thielavia subthermophila, a dematiaceous thermophilic fungus in the order Sordariales, and present a review of previous infections from this order. The patient failed amphotericin B therapy combined with surgical excision despite the drug's low MICs in vitro.

SUBMITTER: Badali H

PROVIDER: S-EPMC3122724 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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Fatal cerebral phaeohyphomycosis in an immunocompetent individual due to Thielavia subthermophila.

Badali Hamid H Chander Jagdish J Gupta Ashish A Rani Hena H Punia Rajpal Singh RS De Hoog G Sybren GS Meis Jacques F JF

Journal of clinical microbiology 20110316 6

We report the first case of fatal brain infection in an Indian farmer caused by Thielavia subthermophila, a dematiaceous thermophilic fungus in the order Sordariales, and present a review of previous infections from this order. The patient failed amphotericin B therapy combined with surgical excision despite the drug's low MICs in vitro. ...[more]

PMID: 21411574

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