Ontology highlight
ABSTRACT:
SUBMITTER: Sheets JJ
PROVIDER: S-EPMC3123041 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Sheets Joel J JJ Hey Tim D TD Fencil Kristin J KJ Burton Stephanie L SL Ni Weiting W Lang Alexander E AE Benz Roland R Aktories Klaus K
The Journal of biological chemistry 20110428 26
Toxin complexes from Xenorhabdus and Photorhabdus spp. bacteria represent novel insecticidal proteins. We purified a native toxin complex (toxin complex 1) from Xenorhabdus nematophilus. The toxin complex is composed of three different proteins, XptA2, XptB1, and XptC1, representing products from class A, B, and C toxin complex genes, respectively. We showed that recombinant XptA2 and co-produced recombinant XptB1 and XptC1 bind together with a 4:1:1 stoichiometry. XptA2 forms a tetramer of ∼1,1 ...[more]