Ontology highlight
ABSTRACT:
SUBMITTER: Broen K
PROVIDER: S-EPMC3125305 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Broen Kelly K Levenga Henriette H Vos Johanna J van Bergen Kees K Fredrix Hanny H Greupink-Draaisma Annelies A Kester Michel M Falkenburg J H Frederik JH de Mulder Pieter P de Witte Theo T Griffioen Marieke M Dolstra Harry H
PloS one 20110628 6
Nonmyeloablative allogeneic stem cell transplantation (SCT) can induce remission in patients with renal cell carcinoma (RCC), but this graft-versus-tumor (GVT) effect is often accompanied by graft-versus-host disease (GVHD). Here, we evaluated minor histocompatibility antigen (MiHA)-specific T cell responses in two patients with metastatic RCC who were treated with reduced-intensity conditioning SCT followed by donor lymphocyte infusion (DLI). One patient had stable disease and emergence of SMCY ...[more]