Ontology highlight
ABSTRACT:
SUBMITTER: Kang H
PROVIDER: S-EPMC3125410 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Kang Huaizhi H Trondoli Anna Carolina AC Zhu Guizhi G Chen Yan Y Chang Ya-Jen YJ Liu Haipeng H Huang Yu-Fen YF Zhang Xiaoling X Tan Weihong W
ACS nano 20110517 6
A near-infrared light-responsive drug delivery platform based on Au-Ag nanorods (Au-Ag NRs) coated with DNA cross-linked polymeric shells was constructed. DNA complementarity has been applied to develop a polyacrylamide-based sol-gel transition system to encapsulate anticancer drugs into the gel scaffold. The Au-Ag NR-based nanogels can also be readily functionalized with targeting moieties, such as aptamers, for specific recognition of tumor cells. When exposed to NIR irradiation, the photother ...[more]