Ontology highlight
ABSTRACT:
SUBMITTER: Dlugosz M
PROVIDER: S-EPMC3125448 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Długosz Maciej M Huber Gary A GA McCammon J Andrew JA Trylska Joanna J
Biopolymers 20110310 9
Protein synthesis on the ribosome involves a number of external protein factors that bind at its functional sites. One key factor is the elongation factor G (EF-G) that facilitates the translocation of transfer RNAs between their binding sites, as well as advancement of the messenger RNA by one codon. The details of the EF-G/ribosome diffusional encounter and EF-G association pathway still remain unanswered. Here, we applied Brownian dynamics methodology to study bimolecular association in the b ...[more]