Unknown

Dataset Information

0

Risk factors for cholangiocarcinoma.


ABSTRACT: Cholangiocarcinoma (CC) is the second most common primary hepatic malignancy after hepatocellular cancer. CC accounts for approximately 10%-25% of all hepatobiliary malignancies. There are considerable geographic and demographic variations in the incidence of CC. There are several established risk factors for CC, including parasitic infections, primary sclerosing cholangitis, biliary-duct cysts, hepatolithiasis, and toxins. Other less-established potential risk factors include inflammatory bowel disease, hepatitis C virus, hepatitis B virus, cirrhosis, diabetes, obesity, alcohol drinking, tobacco smoking, and host genetic polymorphisms. In studies where the distinction between intra- and extrahepatic CC was used, some potential risk factors seem to have a differential effect on CC, depending on the site. Therefore, the consistent use of a more refined classification would allow a better understanding of risk factors for CC.

SUBMITTER: Tyson GL 

PROVIDER: S-EPMC3125451 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

Risk factors for cholangiocarcinoma.

Tyson Gia L GL   El-Serag Hashem B HB  

Hepatology (Baltimore, Md.) 20110701 1


Cholangiocarcinoma (CC) is the second most common primary hepatic malignancy after hepatocellular cancer. CC accounts for approximately 10%-25% of all hepatobiliary malignancies. There are considerable geographic and demographic variations in the incidence of CC. There are several established risk factors for CC, including parasitic infections, primary sclerosing cholangitis, biliary-duct cysts, hepatolithiasis, and toxins. Other less-established potential risk factors include inflammatory bowel  ...[more]

Similar Datasets

| S-EPMC2504381 | biostudies-other
| S-EPMC8672081 | biostudies-literature
| S-EPMC3565026 | biostudies-literature
| S-EPMC8683178 | biostudies-literature
| S-EPMC3718690 | biostudies-other
| S-EPMC6737003 | biostudies-literature
| S-EPMC3804834 | biostudies-literature
| S-EPMC6643449 | biostudies-literature
| S-EPMC7541380 | biostudies-literature
| S-EPMC5995727 | biostudies-literature