Ontology highlight
ABSTRACT:
SUBMITTER: Guerra MT
PROVIDER: S-EPMC3125477 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Guerra Mateus T MT Fonseca Emerson A EA Melo Flavia M FM Andrade Viviane A VA Aguiar Carla J CJ Andrade Lídia M LM Pinheiro Ana Cristina N AC Casteluber Marisa C F MC Resende Rodrigo R RR Pinto Mauro C X MC Fernandes Simone O A SO Cardoso Valbert N VN Souza-Fagundes Elaine M EM Menezes Gustavo B GB de Paula Ana M AM Nathanson Michael H MH Leite Maria de Fátima Mde F
Hepatology (Baltimore, Md.) 20110701 1
<h4>Unlabelled</h4>Subcellular Ca(2+) signals control a variety of responses in the liver. For example, mitochondrial Ca(2+) (Ca(mit)(2+)) regulates apoptosis, whereas Ca(2+) in the nucleus regulates cell proliferation. Because apoptosis and cell growth can be related, we investigated whether Ca(mit)(2+) also affects liver regeneration. The Ca(2+)-buffering protein parvalbumin, which was targeted to the mitochondrial matrix and fused to green fluorescent protein, was expressed in the SKHep1 live ...[more]