MirAct: a web tool for evaluating microRNA activity based on gene expression data.
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ABSTRACT:
SUBMITTER: Liang Z
PROVIDER: S-EPMC3125759 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Publications
mirAct: a web tool for evaluating microRNA activity based on gene expression data.
Liang Zhi Z Zhou Hong H He Zongxiao Z Zheng Haoran H Wu Jiarui J
Nucleic acids research 20110519 Web Server issue
MicroRNAs (miRNAs) are critical regulators in the complex cellular networks. The mirAct web server (http://sysbio.ustc.edu.cn/software/mirAct) is a tool designed to investigate miRNA activity based on gene-expression data by using the negative regulation relationship between miRNAs and their target genes. mirAct supports multiple-class data and enables clustering analysis based on computationally determined miRNA activity. Here, we describe the framework of mirAct, demonstrate its performance by ...[more]
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