MRNA 5'-leader trans-splicing in the chordates.
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ABSTRACT:
SUBMITTER: Vandenberghe AE
PROVIDER: S-EPMC312621 | biostudies-literature | 2001 Feb
REPOSITORIES: biostudies-literature
Publications
mRNA 5'-leader trans-splicing in the chordates.
Vandenberghe A E AE Meedel T H TH Hastings K E KE
Genes & development 20010201 3
We report the discovery of mRNA 5'-leader trans-splicing (SL trans-splicing) in the chordates. In the ascidian protochordate Ciona intestinalis, the mRNAs of at least seven genes undergo trans-splicing of a 16-nucleotide 5'-leader apparently derived from a 46-nucleotide RNA that shares features with previously characterized splice donor SL RNAs. SL trans-splicing was known previously to occur in several protist and metazoan phyla, however, this is the first report of SL trans-splicing within the ...[more]
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