Ontology highlight
ABSTRACT:
SUBMITTER: de Villiers EM
PROVIDER: S-EPMC3126604 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Journal of virology 20110518 14
The family Anelloviridae comprises torque teno viruses (TTVs) diverse in genome structure and organization. The isolation of a large number of TTV genomes (TTV Heidelberg [TTV-HD]) of 26 TTV types is reported. Several isolates from the same type indicate sequence variation within open reading frame 1 (ORF1), resulting in considerably modified open reading frames. We demonstrate in vitro replication of 12 full-length genomes of TTV-HD in 293TT cells. Propagation of virus was achieved by several r ...[more]