Ontology highlight
ABSTRACT:
SUBMITTER: Tan ZJ
PROVIDER: S-EPMC3127172 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Tan Zhi-Jie ZJ Chen Shi-Jie SJ
Biophysical journal 20110701 1
Accurate quantification of the ionic contribution to RNA folding stability could greatly enhance our ability to understand and predict RNA functions. Recently, motivated by the potential importance of ion correlation and fluctuation in RNA folding, we developed the tightly bound ion (TBI) model. Extensive experimental tests showed that the TBI model can lead to better treatment of multivalent ions than the Poisson-Boltzmann equation. In this study, we use the model to quantify the contribution o ...[more]