Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC3129141 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Zhang Yan Y Gladyshev Vadim N VN
The Journal of biological chemistry 20110512 27
Biological trace elements are needed in small quantities but are used by all living organisms. A growing list of trace element-dependent proteins and trace element utilization pathways highlights the importance of these elements for life. In this minireview, we focus on recent advances in comparative genomics of trace elements and explore the evolutionary dynamics of the dependence of user proteins on these elements. Many zinc protein families evolved representatives that lack this metal, wherea ...[more]