Unknown

Dataset Information

0

Sensitive luciferin derived probes for selective carboxypeptidase activity.

ABSTRACT: Highly selective luminescent probes, QLUC-TYR and LUC-GLU, for detection of carboxypeptidase activity were synthesized. Caged substrates were first cleaved by corresponding carboxypeptidases, and then they were activated by luciferase to emit light. Enzymatic activities of biologically important carboxypeptidases can be determined using this technology.

SUBMITTER: Chang YC 

PROVIDER: S-EPMC3129288 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Sensitive luciferin derived probes for selective carboxypeptidase activity.

Chang Yu-Cheng YC   Chao Pei-Wen PW   Tung Ching-Hsuan CH  

Bioorganic & medicinal chemistry letters 20110514 13

Highly selective luminescent probes, QLUC-TYR and LUC-GLU, for detection of carboxypeptidase activity were synthesized. Caged substrates were first cleaved by corresponding carboxypeptidases, and then they were activated by luciferase to emit light. Enzymatic activities of biologically important carboxypeptidases can be determined using this technology. ...[more]

Similar Datasets

Unknown Quinoline-Derived Two-Photon-Sensitive Octupolar Probes.
| S-EPMC5641908 | biostudies-other
Unknown Magnolol dimer-derived fragments as PPAR?-selective probes.
| S-EPMC6180429 | biostudies-literature
Unknown Environment-Sensitive Fluorescent Labelling of Peptides by Luciferin Analogues.
| S-EPMC8706149 | biostudies-literature
Unknown Highly Sensitive "Off/On" EPR Probes to Monitor Enzymatic Activity.
| S-EPMC9314618 | biostudies-literature
Unknown A panel of subunit-selective activity-based proteasome probes.
| S-EPMC3042124 | biostudies-literature
Unknown Elucidating the Quenching Mechanism in Carbon Dot-Metal Interactions-Designing Sensitive and Selective Optical Probes.
| S-EPMC7922893 | biostudies-literature
Unknown A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging.
| S-EPMC4911627 | biostudies-literature
Unknown Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases.
| S-EPMC8341922 | biostudies-literature
Unknown Synthesis of Fluorescent Carbon Dots as Selective and Sensitive Probes for Cupric Ions and Cell Imaging.
| S-EPMC6539694 | biostudies-literature
Unknown Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A(2).
| S-EPMC3549684 | biostudies-literature