Reduced gray matter in the anterior cingulate gyrus in familial schizophrenia: a preliminary report.
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ABSTRACT:
SUBMITTER: Costain G
PROVIDER: S-EPMC3129334 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
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Reduced gray matter in the anterior cingulate gyrus in familial schizophrenia: a preliminary report.
Costain Gregory G Ho Andrew A Crawley Adrian P AP Mikulis David J DJ Brzustowicz Linda M LM Chow Eva W C EW Bassett Anne S AS
Schizophrenia research 20100716 1-3
Few brain imaging studies of schizophrenia involve samples with enhanced genetic homogeneity. We compared MRI volumetric data between individuals with 1q21-q23 linked familial schizophrenia associated with NOS1AP and their first and second degree unaffected relatives. We found significant gray matter reductions in the anterior cingulate gyrus in both affected individuals and their unaffected first degree relatives when compared with their unaffected second degree relatives. These results suggest ...[more]
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