The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics.
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ABSTRACT:
SUBMITTER: Gianoulis TA
PROVIDER: S-EPMC3129682 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics.
Gianoulis Tara A TA Agarwal Ashish A Snyder Michael M Gerstein Mark B MB
Genome biology 20110331 3
Biological data is often tabular but finding statistically valid connections between entities in a sequence of tables can be problematic--for example, connecting particular entities in a drug property table to gene properties in a second table, using a third table associating genes with drugs. Here we present an approach (CRIT) to find connections such as these and show how it can be applied in a variety of genomic contexts including chemogenomics data. ...[more]
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