Ontology highlight
ABSTRACT:
SUBMITTER: Brookes KJ
PROVIDER: S-EPMC3132592 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100922 8
Previous studies in animals and humans have implicated the X-chromosome STS gene in the etiology of attentional difficulties and attention deficit hyperactivity disorder (ADHD). This family based association study has fine mapped a region of the STS gene across intron 1 and 2 previously associated with ADHD, in an extended sample of 450 ADHD probands and their parents. Significant association across this region is demonstrated individually with 7 of the 12 genotyped SNPs, as well as an allele sp ...[more]