Ontology highlight
ABSTRACT:
SUBMITTER: Hancock MJ
PROVIDER: S-EPMC3132596 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Small (Weinheim an der Bergstrasse, Germany) 20110225 7
A simple and inexpensive method is presented employing passive mechanisms to generate centimeters-long gradients of molecules and particles in under a second with only a coated glass slide and a micropipette. A drop of solution is pipetted onto a fluid stripe held in place on a glass slide by a hydrophobic boundary. The resulting difference in curvature pressure drives the flow and creates a concentration gradient by convection. Experiments and theoretical models characterize the flows and gradi ...[more]