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Complete genome sequence of Mycoplasma haemofelis, a hemotropic mycoplasma.

ABSTRACT: Here, we present the genome sequence of Mycoplasma haemofelis strain Langford 1, representing the first hemotropic mycoplasma (hemoplasma) species to be completely sequenced and annotated. Originally isolated from a cat with hemolytic anemia, this strain induces severe hemolytic anemia when inoculated into specific-pathogen-free-derived cats. The genome sequence has provided insights into the biology of this uncultivatable hemoplasma and has identified potential molecular mechanisms underlying its pathogenicity.

SUBMITTER: Barker EN

PROVIDER: S-EPMC3133020 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

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Complete genome sequence of Mycoplasma haemofelis, a hemotropic mycoplasma.

Barker Emily N EN Helps Chris R CR Peters Iain R IR Darby Alistair C AC Radford Alan D AD Tasker Séverine S

Journal of bacteriology 20110211 8

Here, we present the genome sequence of Mycoplasma haemofelis strain Langford 1, representing the first hemotropic mycoplasma (hemoplasma) species to be completely sequenced and annotated. Originally isolated from a cat with hemolytic anemia, this strain induces severe hemolytic anemia when inoculated into specific-pathogen-free-derived cats. The genome sequence has provided insights into the biology of this uncultivatable hemoplasma and has identified potential molecular mechanisms underlying i ...[more]

PMID: 21317334

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