Ontology highlight
ABSTRACT:
SUBMITTER: Byrne JP
PROVIDER: S-EPMC3133057 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Byrne James P JP Morona Judy K JK Paton James C JC Morona Renato R
Journal of bacteriology 20110304 9
A number of single amino acid substitutions throughout Streptococcus pneumoniae Cps2C were found to affect its function and confer either a mucoid or a small colony phenotype. These mutants exhibit significant changes in capsular polysaccharide (CPS) profile relative to that of wild-type pneumococci. The introduced mutations affect either polymerization or ligation of CPS to the cell wall and/or Cps2D phosphorylation. ...[more]