Ontology highlight
ABSTRACT:
SUBMITTER: Kawai M
PROVIDER: S-EPMC3135105 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Nature reviews. Drug discovery 20110201 2
Osteoporosis, a syndrome characterized by thin bones and fractures, has become more prevalent in both women and men. Established therapies for treating this disorder consist primarily of drugs that prevent bone loss, such as the bisphosphonates and selective oestrogen receptor modulators. Although these drugs have been shown to reduce fractures in randomized trials, there is an urgent need for treatments that could lower fracture risk further without additional adverse effects. The introduction ...[more]