Tyrosine kinase signaling in kidney glomerular podocytes.
Ontology highlight
ABSTRACT:
SUBMITTER: Hattori S
PROVIDER: S-EPMC3135133 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Tyrosine kinase signaling in kidney glomerular podocytes.
Hattori Seisuke S Kanda Shoichiro S Harita Yutaka Y
Journal of signal transduction 20110530
During the last decade, several key molecules have been identified as essential components for the filtration barrier function of kidney glomerular podocytes. Mutations in genes encoding these molecules severely impair the podocyte architecture in the affected patients, leading to the development of proteinuria. Extensive investigations have been performed on the function of these molecules, which highlights the importance of tyrosine kinase signaling in the podocytes. An Src family tyrosine kin ...[more]
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