Ontology highlight
ABSTRACT:
SUBMITTER: Bowman WP
PROVIDER: S-EPMC3136564 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Bowman W Paul WP Larsen Eric L EL Devidas Meenakshi M Linda Stephen B SB Blach Laurie L Carroll Andrew J AJ Carroll William L WL Pullen D Jeanette DJ Shuster Jonathan J Willman Cheryl L CL Winick Naomi N Camitta Bruce M BM Hunger Stephen P SP Borowitz Michael J MJ
Pediatric blood & cancer 20110225 4
<h4>Background</h4>The augmented BFM regimen improves outcome for children with NCI high acute lymphoblastic leukemia (ALL). Patient age, sex, and presenting white blood cell count (WBC) can be used to identify a subset of approximately 12% of children with B-precursor ALL that had a 5-year continuous complete remission (CCR) rate of only about 50% on earlier Pediatric Oncology Group (POG) trials.<h4>Procedures</h4>Children's Oncology Group trial P9906 evaluated a modified augmented BFM regimen ...[more]