Searching for an effective, safe and universal anti-HIV vaccine: Finding the answer in just one short peptide.
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ABSTRACT:
SUBMITTER: Lucchese G
PROVIDER: S-EPMC3136904 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Publications
Searching for an effective, safe and universal anti-HIV vaccine: Finding the answer in just one short peptide.
Lucchese Guglielmo G Stufano Angela A Kanduc Darja D
Self/nonself 20110101 1
We explore the pentapeptide overlapping between human immunodeficiency virus (HIV) proteins and the human proteome. Our intent was to define viral peptides to be used in vaccines effective against different HIV strains, vaccines that are able to overcome the difficulties posed by the tendency of HIV to mutate, and that are also exempt from harmful collateral cross-reactions, as well as being repeatedly administrable to the global population. Analysis of HIV-1 envelope glycoprotein 160 (Env gp160 ...[more]
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