Ontology highlight
ABSTRACT:
SUBMITTER: Zhu M
PROVIDER: S-EPMC3138308 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Zhu Mingshe M Zhang Haiying H Humphreys W Griffith WG
The Journal of biological chemistry 20110601 29
Mass spectrometry plays a key role in drug metabolite identification, an integral part of drug discovery and development. The development of high-resolution (HR) MS instrumentation with improved accuracy and stability, along with new data processing techniques, has improved the quality and productivity of metabolite identification processes. In this minireview, HR-MS-based targeted and non-targeted acquisition methods and data mining techniques (e.g. mass defect, product ion, and isotope pattern ...[more]