Ontology highlight
ABSTRACT:
SUBMITTER: Januszyk K
PROVIDER: S-EPMC3138715 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Januszyk Kurt K Lima Christopher D CD
Advances in experimental medicine and biology 20100101
A large body of structural work conducted over the past ten years has elucidated mechanistic details related to 3' to 5' processing and decay of RNA substrates by the RNA exosome. This chapter will focus on the structural organization of eukaryotic exosomes and their evolutionary cousins in bacteria and archaea with an emphasis on mechanistic details related to substrate recognition and to 3' to 5' phosphorolytic exoribonucleolytic activities of bacterial and archaeal exosomes as well as the hyd ...[more]