Ontology highlight
ABSTRACT:
SUBMITTER: Prentice JS
PROVIDER: S-EPMC3140468 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Prentice Jason S JS Homann Jan J Simmons Kristina D KD Tkačik Gašper G Balasubramanian Vijay V Nelson Philip C PC
PloS one 20110720 7
We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes overlap, and accounts for intrinsic variability of spikes from each unit. As MEAs grow larger, it is important to find spike-identification methods that are scalable, that is, the computational cost of spike fitting should scale well with the number of units observed. Our algorithm accomplishes thi ...[more]