Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC3140481 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Liu Xinyu X Fernandes Roxanne R Gertsenstein Marina M Perumalsamy Alagammal A Lai Ingrid I Chi Maggie M Moley Kelle H KH Greenblatt Ellen E Jurisica Igor I Casper Robert F RF Sun Yu Y Jurisicova Andrea A
PloS one 20110720 7
Progression of fertilized mammalian oocytes through cleavage, blastocyst formation and implantation depends on successful implementation of the developmental program, which becomes established during oogenesis. The identification of ooplasmic factors, which are responsible for successful embryo development, is thus crucial in designing possible molecular therapies for infertility intervention. However, systematic evaluation of molecular targets has been hampered by the lack of techniques for eff ...[more]