Ontology highlight
ABSTRACT:
SUBMITTER: Gullberg E
PROVIDER: S-EPMC3141051 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Gullberg Erik E Cao Sha S Berg Otto G OG Ilbäck Carolina C Sandegren Linus L Hughes Diarmaid D Andersson Dan I DI
PLoS pathogens 20110721 7
The widespread use of antibiotics is selecting for a variety of resistance mechanisms that seriously challenge our ability to treat bacterial infections. Resistant bacteria can be selected at the high concentrations of antibiotics used therapeutically, but what role the much lower antibiotic concentrations present in many environments plays in selection remains largely unclear. Here we show using highly sensitive competition experiments that selection of resistant bacteria occurs at extremely lo ...[more]