Ontology highlight
ABSTRACT:
SUBMITTER: Watkins NN
PROVIDER: S-EPMC3141315 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Watkins Nicholas N NN Sridhar Supriya S Cheng Xuanhong X Chen Grace D GD Toner Mehmet M Rodriguez William W Bashir Rashid R
Lab on a chip 20110201 8
We have developed a microfabricated biochip that enumerates CD4+ T lymphocytes from leukocyte populations obtained from human blood samples using electrical impedance sensing and immunoaffinity chromatography. T cell counts are found by obtaining the difference between the number of leukocytes before and after depleting CD4+ T cells with immobilized antibodies in a capture chamber. This differential counting technique has been validated to analyze physiological concentrations of leukocytes with ...[more]