Ontology highlight
ABSTRACT:
SUBMITTER: Lemaire M
PROVIDER: S-EPMC3143470 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Lemaire Maryse M Lemarié Catherine A CA Molina Manuel Flores MF Schiffrin Ernesto L EL Lehoux Stéphanie S Mann Koren K KK
Toxicological sciences : an official journal of the Society of Toxicology 20110421 1
Arsenic is a widespread environmental contaminant to which millions of people are exposed worldwide. Exposure to arsenic is epidemiologically linked to increased cardiovascular disease, such as atherosclerosis. However, the effects of moderate concentrations of arsenic on atherosclerosis formation are unknown. Therefore, we utilized an in vivo ApoE(-/-) mouse model to assess the effects of chronic moderate exposure to arsenic on plaque formation and composition in order to facilitate mechanistic ...[more]