Influence of BMI on level of circulating progenitor cells.
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ABSTRACT:
SUBMITTER: Bellows CF
PROVIDER: S-EPMC3143489 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Influence of BMI on level of circulating progenitor cells.
Bellows Charles F CF Zhang Yan Y Simmons Paul J PJ Khalsa Amrit S AS Kolonin Mikhail G MG
Obesity (Silver Spring, Md.) 20110203 8
Obesity complicates a number of diseases through mechanisms that are poorly defined. Mobilization and recruitment of progenitor cells to pathological sites is an important factor in disease progression. Here, we analyzed the influence of obesity on the systemic circulation of CD34(+) cell populations and correlated frequencies of cells displaying previously established cell marker signatures with the BMI. Comparative analysis of peripheral blood mononuclear cells (PBMC) from 12 nonobese (BMI <30 ...[more]
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