Ontology highlight
ABSTRACT:
SUBMITTER: Steenhuis P
PROVIDER: S-EPMC3144102 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Steenhuis P P Huntley R E RE Gurenko Z Z Yin L L Dale B A BA Fazel N N Isseroff R R RR
Journal of dental research 20101202 2
Catecholamines are present in saliva, but their influence on oral epithelium is not understood. Because psychological stress increases salivary catecholamines and impairs oral mucosal wound healing, we sought to determine if epithelial adrenergic signaling could link these two findings. We found that cultured human oral keratinocytes (HOK) express the α(2B)- and β(2)-adrenergic receptors (ARs). Exposure of HOK to either epinephrine or the β-AR agonist, isoproterenol, reduced migratory speed and ...[more]