The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery.
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ABSTRACT:
SUBMITTER: Schaafsma BE
PROVIDER: S-EPMC3144993 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Publications
The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery.
Schaafsma Boudewijn E BE Mieog J Sven D JS Hutteman Merlijn M van der Vorst Joost R JR Kuppen Peter J K PJ Löwik Clemens W G M CW Frangioni John V JV van de Velde Cornelis J H CJ Vahrmeijer Alexander L AL
Journal of surgical oncology 20110414 3
Optical imaging using near-infrared (NIR) fluorescence provides new prospects for general and oncologic surgery. ICG is currently utilised in NIR fluorescence cancer-related surgery for three indications: sentinel lymph node (SLN) mapping, intraoperative identification of solid tumours, and angiography during reconstructive surgery. Therefore, understanding its advantages and limitations is of significant importance. Although non-targeted and non-conjugatable, ICG appears to be laying the founda ...[more]
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