Ontology highlight
ABSTRACT:
SUBMITTER: Giannopoulou EG
PROVIDER: S-EPMC3145611 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Giannopoulou Eugenia G EG Elemento Olivier O
BMC bioinformatics 20110707
<h4>Background</h4>Chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq), enables unbiased and genome-wide mapping of protein-DNA interactions and epigenetic marks. The first step in ChIP-seq data analysis involves the identification of peaks (i.e., genomic locations with high density of mapped sequence reads). The next step consists of interpreting the biological meaning of the peaks through their association with known genes, pathways, regulatory elements, and integra ...[more]