Genus-specific substitution rate variability among picornaviruses.
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ABSTRACT:
SUBMITTER: Hicks AL
PROVIDER: S-EPMC3147923 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Genus-specific substitution rate variability among picornaviruses.
Hicks Allison L AL Duffy Siobain S
Journal of virology 20110525 15
Picornaviruses have some of the highest nucleotide substitution rates among viruses, but there have been no comparisons of evolutionary rates within this broad family. We combined our own Bayesian coalescent analyses of VP1 regions from four picornaviruses with 22 published VP1 rates to produce the first within-family meta-analysis of viral evolutionary rates. Similarly, we compared our rate estimates for the RNA polymerase 3D(pol) gene from five viruses to four published 3D(pol) rates. Both a s ...[more]
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