Ontology highlight
ABSTRACT:
SUBMITTER: Khodthong C
PROVIDER: S-EPMC3148490 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Khodthong Chuenchanok C Kabachinski Greg G James Declan J DJ Martin Thomas F J TF
Cell metabolism 20110801 2
Neuropeptide and peptide hormone secretion from neural and endocrine cells occurs by Ca(2+)-triggered dense-core vesicle exocytosis. The membrane fusion machinery consisting of vesicle and plasma membrane SNARE proteins needs to be assembled for Ca(2+)-triggered vesicle exocytosis. The related Munc13 and CAPS/UNC31 proteins that prime vesicle exocytosis are proposed to promote SNARE complex assembly. CAPS binds SNARE proteins and stimulates SNARE complex formation on liposomes, but the relevance ...[more]