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Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.

ABSTRACT: BACKGROUND: Several studies conducted during the past two decades suggested increasing trend of childhood allergic diseases in China. However, few studies have provided detailed description of geographic variation and explored risk factors of these diseases. This study investigated the pattern and risk factors of asthma, allergic rhinitis and eczema in eight metropolitan cities in China. METHODS: We conducted a cross-sectional survey during November-December 2005 in eight metropolitan cities in China. A total of 23791 children aged 6-13 years participated in this survey. Questions from the standard questionnaire of the International Study of Asthma and Allergies in Children (ISAAC) were used to examine the pattern of current asthma, allergic rhinitis and eczema. Logistic regression analyses were performed to assess the risk factors for childhood allergies. RESULTS: The average prevalence of childhood asthma, allergic rhinitis and eczema across the eight cities was 3.3% (95% Confidence interval (CI): 3.1%, 3.6%), 9.8% (95% CI: 9.4%, 10.2%) and 5.5% (95% CI: 5.2%, 5.8%), respectively. Factors related to lifestyle, mental health and socio-economic status were found to be associated with the prevalence of childhood allergies. These risk factors were unevenly distributed across cities and disproportionately affected the local prevalence. CONCLUSIONS: There was apparent geographic variation of childhood allergies in China. Socio-environmental factors had strong impacts on the prevalence of childhood allergies; but these impacts differed across regions. Thus public health policies should specifically target at the local risk factors for each individual area.

SUBMITTER: Li F

PROVIDER: S-EPMC3148998 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.

Li Fei F Zhou Yingchun Y Li Shenghui S Jiang Fan F Jin Xingming X Yan Chonghuai C Tian Ying Y Zhang Yiwen Y Tong Shilu S Shen Xiaoming X

BMC public health 20110606

<h4>Background</h4>Several studies conducted during the past two decades suggested increasing trend of childhood allergic diseases in China. However, few studies have provided detailed description of geographic variation and explored risk factors of these diseases. This study investigated the pattern and risk factors of asthma, allergic rhinitis and eczema in eight metropolitan cities in China.<h4>Methods</h4>We conducted a cross-sectional survey during November-December 2005 in eight metropolit ...[more]

PMID: 21645361

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Project description:BACKGROUND:Allergic diseases, such as asthma, dermatitis, rhinitis, and eczema, are highly prevalent in Chinese school children. Environmental factors, including air pollution and automobile exhaust, play an important role in the etiology of these diseases. However, prenatal and neonatal factors, such as gender, maternal diseases during pregnancy, and premature birth, may also be associated with allergic disease occurrence. The objective of this study was to explore prenatal and neonatal factors that are involved in the development of allergic diseases among primary and middle school students in Guangzhou, China. METHODS:A cross-sectional survey was launched by the Health Promotion Centre for Primary and Secondary Schools of the Guangzhou Municipality in October 2017. All primary and middle school students in Guangzhou were notified to participate in the questionnaire online under the direction of their parents. The results of the physical examination were reported by the schools' medical department. The results of the questionnaire were collected and analyzed by the researchers. The prevalence of asthma, allergic rhinitis, allergic dermatitis, and eczema was identified. RESULTS:Based on reported 183,449 questionnaires and medical records, the data indicate that the sex, birth weight, neonatal feeding type, delivery mode, and students' father smoking status were significantly associated with the prevalence of all four allergic diseases in primary and middle school children. In further stratified analyses of the children with normal birth weight (2500-4000 g) and without any maternal diseases during pregnancy, the factors of male sex, high birth weight, cesarean delivery, and father smoking status all increased the risk of asthma, dermatitis, rhinitis, and eczema. Also, unlike exclusive breastfeeding, breast plus formula feeding increased these risks, but pure formula feeding had the opposite effect. CONCLUSION:Prenatal and neonatal factors, including male sex, high birth weight, cesarean delivery, only child, and father smoking status are associated with the risks of allergic diseases in school children.

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Project description:Confirmed cases of coronavirus in Africa, particularly in Ethiopia, are increasing rapidly following improved testing. This study is aimed at assessing the perceptions and practices towards coronavirus among the metropolitan city population of Amhara region, Ethiopia, and examining the associated factors affecting public perceptions and practices regarding coronavirus among the population of metropolitan cities. A total of 1288 randomly selected participants completed a questionnaire designed to assess perceptions and practices towards coronavirus and associated factors. The statistical analysis involved fitting a binary logistic regression model and a chi-square test. Of 1288 study participants, 788 (61.2%) and 500 (38.8%) were male and female, respectively. Their average age and monthly income were 29.2 years and 2484 birr, respectively. Preventive measures followed by the participants involved washing hands with soap and water rubbing for at least 20 s (55.4%) and visiting a doctor when corona symptoms show up (49.5%). Permanent rural residents had lower odds of good perception and practices regarding coronavirus (aOR=0.505; 95% CI=0.15, 0.82) as compared to permanent urban resident participants. Due to misguided perceptions and practices, the prevalence of coronavirus in metropolitan city communities of Amhara region is high. The city of residence, marital status, educational level, permanent residence, and information sources were significantly associated with people's perceptions and practices towards the prevention of coronavirus. Perceptions and practices towards coronavirus had a significant positive correlation in terms of preventive measures against coronavirus. Therefore, the authors would like to recommend if substantive effort from the government and different stakeholders regarding to raising the perception and practices of communities in the cities towards the pandemic and reduce the collateral damage especially the lower income communities who cannot afford basic needs.

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Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.

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Prevalence and risk factors of childhood allergic diseases in eight metropolitan cities in China: a multicenter study.

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