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Benzyl N-(1-{N'-[(E)-2-chloro-benzyl-idene]hydrazinecarbon-yl}-2-hy-droxy-eth-yl)carbamate.

ABSTRACT: The mol-ecule of the title compound, C(18)H(18)ClN(3)O(4), is twisted about the chiral C atom with the dihedral angle between the two amide residues being 87.8 (5)°, but, overall, it can be described as curved, with the benzene rings lying on the same side of the mol-ecule [dihedral angle = 62.8 (4)°]. The conformation about the imine bond [1.294 (7) Å] is E. In the crystal, a two-dimensional array in the ab plane is mediated by O-H⋯O and N-H⋯O hydrogen bonds as well as C-H⋯Cl inter-actions. The layers stack along the c-axis direction, being connected by C-H⋯.π contacts.

SUBMITTER: de Souza MV

PROVIDER: S-EPMC3151956 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Benzyl N-(2-hy-droxy-1-{N'-[(1E)-2-hy-droxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.

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Project description:The carbamate and hydrazone groups in the title compound, C(18)H(18)N(4)O(6), are approximately orthogonal [dihedral angle = 83.3 (4)°], and the carbonyl groups are effectively anti [O=C⋯C=O torsion angle = -116.2 (7)°]. The conformation about the imine bond [1.295 (11) Å] is E. The crystal packing is dominated by O-H⋯O and N-H⋯O hydrogen bonding, which leads to two-dimensional arrays in the ab plane.

| S-EPMC3007287 | biostudies-literature

tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(1E)-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.

Project description:The mol-ecule of the title compound, C(16)H(23)N(3)O(5), is twisted about the chiral C atom, the dihedral angle formed between the amide residues being 79.6?(3)°. The conformation about the imine bond [1.278?(5)?Å] is E. In the crystal, O-H?O and N-H?O hydrogen bonding between the hy-droxy, amine and carbonyl groups leads to the formation of supra-molecular layers, which stack along the c-axis direction.

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Project description:A U-shaped conformation is found in the title compound, C(19)H(21)N(3)O(5), with the benzene rings lying to the same side of the mol-ecule; the dihedral angle between them is 10.83 (16)°. The dihedral angle formed between the hydrazinecarbonyl and carbamate residues is 68.42 (13)°. The carbonyl groups lie approximately at right angles to each other [O-C⋯C-O pseudo torsion angle of 107.7 (3)°], and the conformation about the C12=N3 bond [1.279 (4) Å] is E. An intra-molecular N(cb)-H⋯O(hy) (cb = carbmate and hy = hydr-oxy) hydrogen bond occurs, generating an S(6) loop. In the crystal, inter-molecular O(h)-H⋯O(ca) (ca = carbon-yl) and N(hz)-H⋯O(ca) (hz = hydrazine) hydrogen bonds lead to the formation of a supra-molecular chain, two mol-ecules thick, which propagates along the a axis; these are connected by C-H⋯O(ca) contacts.

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Project description:In the title compound, C(16)H(15)ClN(2)O(3)·H(2)O, the water mol-ecule is linked to the Schiff base mol-ecule via an O-H⋯O hydrogen bond. In the Schiff base mol-ecule, an intramolecular O-H⋯N hydrogen bond occurs and the dihedral angle between the two benzene rings is 20.5 (5)°. In the crystal, the Schiff base and water mol-ecules are linked by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds, forming layers in the ab plane.

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A new polymorph of N-(2-{N'-[(1E)-2-hy-droxy-benzyl-idene]hydrazinecarbon-yl}phen-yl)benzamide.

Project description:The title compound, C21H17N3O3, is a new polymorph of an already published structure [Shashidhar et al. (2006 ?). Acta Cryst. E62, o4473-o4475]. The previously reported structure crystallizes in the monoclinic space group C2/c, whereas the structure reported here is in the tetra-gonal space group I41/a. The bond lengths and angles are similar in both structures. The mol-ecule adopts an extended conformation via intra-molecular N-H?O and O-H?N hydrogen bonds; the terminal phenyl ring and the hy-droxy-lphenyl ring are twisted with respect to the central benzene ring by 44.43?(7) and 21.99?(8)°, respectively. In the crystal, mol-ecules are linked by N-H?O hydrogen bonds, weak C-H?O hydrogen bonds and weak C-H?? inter-actions into a three-dimensional supra-molecular network.

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