Management options in triple-negative breast cancer.
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ABSTRACT:
SUBMITTER: Minami CA
PROVIDER: S-EPMC3153117 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Management options in triple-negative breast cancer.
Minami Christina A CA Chung Debra U DU Chang Helena R HR
Breast cancer : basic and clinical research 20110727
Notorious for its poor prognosis and aggressive nature, triple-negative breast cancer (TNBC) is a heterogeneous disease entity. The nature of its biological specificity, which is similar to basal-like cancers, tumors arising in BRCA1 mutation carriers, and claudin-low cancers, is currently being explored in hopes of finding the targets for novel biologics and chemotherapeutic agents. In this review, we aim to give a broad overview of the disease's nomenclature and epidemiology, as well as the ba ...[more]
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