Ontology highlight
ABSTRACT:
SUBMITTER: Qi J
PROVIDER: S-EPMC3153456 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Qi Jinpeng J Ding Yongsheng Y Zhu Ying Y Wu Yizhi Y
PloS one 20110809 8
Under acute perturbations from outer environment, a normal cell can trigger cellular self-defense mechanism in response to genome stress. To investigate the kinetics of cellular self-repair process at single cell level further, a model of DNA damage generating and repair is proposed under acute Ion Radiation (IR) by using mathematical framework of kinetic theory of active particles (KTAP). Firstly, we focus on illustrating the profile of Cellular Repair System (CRS) instituted by two sub-populat ...[more]