Ontology highlight
ABSTRACT:
SUBMITTER: Sehgal A
PROVIDER: S-EPMC3153991 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Cell 20110701 2
Sleep remains one of the least understood phenomena in biology--even its role in synaptic plasticity remains debatable. Since sleep was recognized to be regulated genetically, intense research has launched on two fronts: the development of model organisms for deciphering the molecular mechanisms of sleep and attempts to identify genetic underpinnings of human sleep disorders. In this Review, we describe how unbiased, high-throughput screens in model organisms are uncovering sleep regulatory mech ...[more]