Ontology highlight
ABSTRACT:
SUBMITTER: Nikolova YS
PROVIDER: S-EPMC3154113 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Nikolova Yuliya S YS Ferrell Robert E RE Manuck Stephen B SB Hariri Ahmad R AR
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110518 9
Research integrating neuroimaging and molecular genetics has yielded important insights into how variability in brain chemistry predicts individual differences in brain function, behavior and related risk for psychopathology. However, existing studies have been limited by their focus on the independent effects of single polymorphisms with modest impact on brain chemistry. Here, we explored the effects of five functional polymorphisms affecting dopamine (DA) signaling on reward-related ventral st ...[more]